Breast Implants Research Today is a free monthly online journal that collates and summarizes the latest research about Breast Implants, including details on silicone implant, breast augmentation, surgery, risks.

Microscopic polyangiitis after silicone breast implantation.

Iyoda M, Ito J, Nagai H, Sato K, Kuroki A, Shibata T, Kitazawa K, Sugisaki T

Department of Nephrology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan, iyoda@med.showa-u.ac.jp

We describe the case of a patient who developed microscopic polyangiitis (MPA) after silicone breast implantation. A 60-year-old woman who had undergone silicone breast implantation was admitted to our hospital with complaints of general malaise and hematoproteinuria. She was diagnosed as having MPA with evidence of acute progressive renal failure, pulmonary hemorrhage, and positivity for myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA). A renal biopsy showed severe necrotizing and crescentic glomerulonephritis with arteriolitis. The patient received high-dose steroids and plasma exchange treatment, but died of progressive pulmonary hemorrhage and multiple cerebral hemorrhage. Silicone implantation is associated with scleroderma, systemic lupus erythematosus, and rheumatoid arthritis. This case report indicates the possibility of the development of MPA after silicone breast implantation.

Published 28 September 2005 in Clin Exp Nephrol, 9(3): 252-4.
Full-text of this article is available online (may require subscription).

© 2005-2008 Breast Implants Research Today. All Rights Reserved.